Yes—a low genetic risk score was the strongest of six clues for identifying older adults whose heart disease risk might be overestimated. Researchers reviewed data from 7,764 people aged 70 and older. The middle age was 74, and 48% were women. None had a prior heart or blood vessel event when they enrolled. All had an estimated 7.5% to 20% chance of an event over 10 years. Those estimates came from PREVENT, a heart disease risk calculator. The team tested whether extra information could identify people with lower risk. One measure was hs-CRP (High-Sensitivity C-Reactive Protein), a blood marker of inflammation. Others included genetic scores, heart-related blood tests, and family history. Over a middle follow-up time of 10.3 years, 725 people had an event. That was 9.3% of the group. A score combining many inherited differences linked to heart artery disease performed best. Scores in the lowest quarter helped place 25.9% of people without events into a lower-risk category correctly. A blood test called high-sensitivity troponin I, which measures a heart muscle protein, ranked second. This was about improving risk estimates, not proving a way to lower risk. The source summary gives no separate performance numbers for the inflammation marker. It therefore cannot tell us how much a low reading changes someone's risk estimate. For BioSocial members, this adds context to tracking bloodwork. A single low result is not the whole picture. Comparing notes alongside age, family history, and other results can keep community discussions grounded. How have your bloodwork results lined up with your heart disease risk estimates?